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Human Cancer Genetics

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Cancer
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Dr Gareth Bond, Associate Member of the Ludwig Institute for Cancer Research, studies the influence of genetic variants on the origins, progression and treatment of human cancer.
SNP - single nucleotide polymorphisms

There is great heterogeneity between individuals in their risk of developing cancer, disease progression and responses to therapy. Specific single nucleotide polymorphisms (SNPs) are associated with human cancers. They have the potential to help us identify individuals more at risk of developing cancer, and better target preventative or therapeutic strategies.

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Cancer

Personalised Medicine

Dr Jenny Taylor is the Programme Director for the Genomic Medicine Theme, Wellcome Trust Centre for Human Genetics. Her research bridges the gap between genetics research and the use of its discoveries in diagnosis or treatment of medical conditions.
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Targeting epigenetics to treat cancer

Transcription is a tightly regulated process, where chemical modifications initiate the duplication of genetic material. This epigenetic process is often dysregulated in cancer, but it can be targeted with small molecule inhibitors.
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Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Cancer
People
Gareth Bond
Keywords
cancer
genetic
single nucleotide polymorphisms
preventative
therapeutic
Department: Nuffield Department of Clinical Medicine
Date Added: 11/03/2015
Duration: 00:05:12

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