Evidence-Based Health Care

The broad aim of the Centre for Evidence Based Medicine is to develop, teach and promote evidence-based health care and provide support and resources to doctors and health care professionals to help maintain the highest standards of medicine.

Many of the talks are taken from the Oxford Evidence-Based Health Care Programme and delivered by members of the Nuffield Department of Primary Care Health Sciences, the Centre of Evidence Medicine and leaders in the field of Evidence-based Health Care internationally.

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Displaying 1 - 100 of 108 episodes

Episode	Description	People	Date
Misunderstandings and misuses of commonly-cited methods for systematic reviews & meta-analyses.	Professor Julian Higgins explains why he believes the systematic review and meta-analysis methods described in many highly cited papers are routinely misunderstood or misused.	Julian Higgins	28 March, 2025
Not just "what," but also "how well:" Intervention fidelity in clinical trials of complex interventions in healthcare	The concepts of intervention fidelity and how they can influence the results of clinical trials.	Arsenio Paez	28 January, 2025
Stein's paradox	Dr Jason Oke, gives a talk on Stein's work, the paradox and some of its more controversial results and consider the implications for evidence-based medicine	Jason Oke	24 October, 2024
How stories shaped every aspect of our mixed methods study	Kirsten Prest discusses the 'Encompass' study on care for disabilities in Uganda and its wider application in the NHS, where narrative-driven mixed methods research shaped phases from grants to implementation	Kirsten Prest	12 July, 2024
Artificial Intelligence and Health Security, managing the risks	Professor Karl Roberts, University of New England, NSW, Australia gives a talk on generative AI and large language models as applied to healthcare.	Karl Roberts	17 April, 2024
Evidence-based dentistry: The building of the Dental Fact Box repository – OHA!	An introduction to OHA!, a tool currently being developed which aims to assist dentists in accessing the most reliable evidence regarding the effectiveness of common dental treatments.	Paulo Nadanovsky	12 October, 2023
Speedy or sloppy?: The opportunities and challenges of rapid qualitative research	Using a variety of examples of fast and slow qualitative research this talk explores the affordances of rapid methods, and help researchers decide if and where to use them in their own work.	Anna Dowrick	30 June, 2023
Realist inquiry in global health practice: trials, tribulations (& triumphs?)	Dr Sara Van Belle, Institute of Tropical Medicine, Antwerp gives a talk on the practice of realist inquiry in global health.	Sara Van Belle	8 June, 2023
Testing usability and impact of the OxRisk prediction models	Professor Seena Fazel, University of Oxford gives a talk on recent advances in prognostic modelling in psychiatry.	Seena Fazel	22 May, 2023
Alcohol and cardiovascular disease: Is moderate drinking really beneficial for cardiovascular disease?	Dr Derrick Bennett, University of Oxford gives a talk on the epidemiological evidence of alcohol and cardiovascular disease.	Derrick Bennett	22 May, 2023
Evidence in Women's Health: Coil contraceptive - what is it and what are the potential harms for women?	In this episode EBHC DPhil Director, Jamie Hartmann-Boyce and Dr. Anne Marie Boylan discuss intrauterine contraception commonly known as the coil.	Jamie Hartmann-Boyce, Anne-Marie Boylan, Neda Taghinejadi, Megan Carter	23 March, 2023
The medical occupational outcomes of military mental health patients. A closed-cohort study	Surgeon Commander Charlotte Evans is Royal Navy Hudson Visiting Fellow at St. Anthony's College and gave a talk about her dissertation work in relation to military mental health patients.	Charlotte Evans	8 March, 2023
Evidence in Women's Health: Evaluating a community singing intervention for postnatal depression	Dr Alexandra Burton reports on the SHAPER-PND study exploring singing's effect on postnatal depression in new mothers	Alexandra Burton	10 February, 2023
Evidence in Women's Health: Why is endometriosis difficult to diagnose?	We discuss evidence around delays in diagnosis of endometriosis and speak with Dr Annalise Weckesser and Dr Sharon Dixon, who have both researched endometriosis from the perspective of women as patients and from that of GPs.	Jamie Hartmann-Boyce, Anne-Marie Boylan, Annalise Weckesser, Sharon Dixon	30 January, 2023
Evidence in Women's Health: Menopause and Hormone Replacement Therapy (HRT) - What are the risks, benefits and experiences for women?	EBHC DPhil Director, Jamie Hartmann-Boyce and Dr. Anne Marie Boylan discuss menopause and hormone replacement therapy (HRT)	Jamie Hartmann-Boyce, Anne-Marie Boylan, Elizabeth Spencer, Carol Coupland	12 January, 2023
Heart Failure in Primary Care: Lessons from Big Data	Dr Clare J Taylor, Academic GP, explores how we can use large, anonymised GP datasets to improve our understanding of heart failure management in primary care.	Clare J Taylor	24 November, 2022
Evidence in Women's Health: Are there higher mortality rates in women who have been operated on by male surgeons?	In 2022 a Canadian population based retrospective cohort study hit the headlines in the U.K. by claiming that women were 32% more likely to die if operated on by a male surgeon.	Carl Heneghan, Jamie Hartmann-Boyce, Anne-Marie Boylan, Sunil Patel, Emily McFadden, Sharon Dixon, Megan Carter	31 October, 2022
Sporadic, late-onset, and multi-stage diseases	Dr Anthony Webster, University of Oxford gives a talk on combining mathematical modelling with big data statistics to distinguish between sporadic, late-onset, and multi-stage diseases.	Anthony Webster	20 October, 2022
How should we teach evidence-based medicine in the 21st century?	Dr Gordon Guyatt provides a guest talk on how we should teach evidence-based medicine in the 21st century	Gordon Guyatt	3 October, 2022
The Role of Social Endometriosis Research in Improving Care and Addressing Intersectional Health Disparities	Dr Annalise Weckesser will discuss her qualitative studies exploring women’s experiences of endometriosis and doctors’ perspectives on treating the condition and how to improve care.	Annalise Weckesser	1 July, 2022
How do you carry out a realist synthesis of an intervention when there's 'no evidence'?	Joanne Greenhalgh, Professor of Applied Social Research Methodology (University of Leeds) on the experiences of conducting a realist synthesis of the feedback of aggregated patient reported outcome measure (PROMs) data to improve patient care.	Joanne Greenhalgh	25 May, 2022
The messy realities of qualitative health research	Dr Anne-Marie Boylan and Dr Laura Griffith, explore the value of qualitative health research and discuss what it's really like to undertake qualitative research.	Anne-Marie Boylan, Laura Griffith	21 May, 2021
Leading and teaching Evidence-Based Health Care	Professor Kamal Mahtani and David Nunan interview Professor Paul Glasziou, Director of the Institute for Evidence-Based Healthcare at Bond University, about his experience of leadership and his work in capacity building through teaching and supervision.	Kamal Mahtani, David Nunan, Paul Glasziou	18 March, 2021
Exploring the fundamentals of leadership with Professor Carl Heneghan - Part Two	Professor Kamal Mahtani continues his interview with Professor Carl Heneghan, discussing where your motivation as a leader comes from, succession planning, seeking mentoring, how leaders can engage with the wider world.	Kamal Mahtani, Carl Heneghan	25 November, 2020
Exploring the fundamentals of leadership with Professor Carl Heneghan - Part One	Professor Kamal Mahtani interviews Professor Carl Heneghan, exploring his leadership; how it all started, the challenges he has faced, emotional intelligence, the importance of clear communication and being a tortoise rather than a hare as a leader.	Carl Heneghan, Kamal Mahtani	4 November, 2020
How do species postpone or even escape from senescence?	Dr Rob Salguero-Gomez, Associate Professor in Ecology, Department of Zoology, gives a talk on lessons for a longer, better human life for the EBHC podcast series.	Rob Salguero-Gomez	2 November, 2020
Overdiagnosis and Lung Cancer Screening	Recent results of the NELSON Lung Cancer Screening Trial reports reductions in lung-cancer survival but not overall survival - The desire to detect disease even earlier means Overdiagnosis is on the rise.	Carl Heneghan	14 February, 2020
When meta-analyses of the same question find different things	Dr Jamie Hartmann-Boyce discusses a case study of systematic reviews of electronic cigarettes for smoking cessation, looking across meta-analyses in this area.	Jamie Hartmann-Boyce	3 February, 2020
Conflicts of Interest in Medicine: Why it’s time for a UK Sunshine Act	Should doctors with commercial interests lead research on their products? Should we forget ‘conflicts’ and discuss ‘declarations of interest’ instead? Who should hold and maintain conflicts of interest registers for doctors?	Carl Heneghan	21 January, 2020
Health Policy Evaluation	Professor Karla Hemming discusses using evidence-based policy in the evaluation of policy interventions and answers the question 'how useful is the stepped-wedge study as an evaluation design?	Karla Hemming	12 December, 2019
Realist research in practice - informing a new TB policy in Georgia	Professor Bruno Marchal gives a talk illustrating the principles of realist evaluation using the case of the development of a new Tuberculosis control policy in Georgia.	Bruno Marchal	29 November, 2019
Evidence isn't enough: The politics and practicalities of communicating health research	The logic and principles behind the drive for evidence-based health care are so compelling that often the limitations of evidence go unacknowledged.	Oli Williams	27 November, 2019
Operationalising the potential of Applied Digital Health research	The increased reliance of health systems on the digital record as the primary mechanism for storing data on consultations and other health interactions has opened new opportunities for research, healthcare innovation, and health policy.	Richard Hobbs	27 November, 2019
Everything is a poison	Professor Jeffrey Aronson, Consultant Physician and Clinical Pharmacologist, Department of Primary Care Health Sciences, gives a talk on dose-response curves for the EBHC podcast series.	Jeffrey Aronson	29 October, 2019
Safe and effective drugs: The need to use all the available evidence to inform the effectiveness of commonly used medicines	Carl Heneghan, Professor of Evidence-Based Medicine, employs evidence-based methods to research diagnostic reasoning, test accuracy and communicating diagnostic results to a wider audience.	Carl Heneghan	21 October, 2019
Diabetes, blood sugar, and red wine: a personal study	This talk was delivered by Martin Bland.	Martin Bland	17 July, 2019
The secret diary of a health ethnographer - what's it really like doing qualitative observation in operating rooms, ambulances, triage call centres and other health care settings?	This guest lecture draws on nearly thirty years' experience of doing qualitative research in a variety of health settings that contain people, blood, injury, disease, emotions, and technologies.	Catherine Pope	3 July, 2019
Big data in heart failure - opportunities and realities	The global health burden of heart failure is high, both as the common end-point for many cardiovascular diseases (e.g. hypertension and heart attacks) and a common point on the trajectory of non-cardiovascular diseases (e.g. chronic respiratory disease).	Amitava Banerjee	3 July, 2019
Behavioural Interventions to Improve the Quality of the Grocery Shopping	This evening lecture is given in conjunction with the Introduction to Study Design and Research Methods accredited short course, part of the Evidence-Based Healthcare programme at the University of Oxford's Department for Continuing Education.	Carmen Piernas	11 June, 2019
The BMJ's open data campaign	Fiona Godlee, Editor in Chief of The BMJ, gives a talk for the EBHC podcast series	Fiona Godlee	13 May, 2019
Using evidence to overcome fake news about healthcare	Professor Carl Heneghan has extensive experience of working with the media. In this talk he will discuss some recent case examples, working with the BBC amongst others.	Carl Heneghan	9 April, 2019
Are we really advancing qualitative methods in health research?	For many good reasons, semi-structured interviews, focus groups, thematic analysis, and realist tales have become key tools within the qualitative researcher's methodological toolkit.	Cassandra Phoenix	8 April, 2019
Size matters a tous les temps, a tous les peuples	Dr. Martyn Sene is Deputy CEO of the National Physical Laboratory (NPL), here, he gives an introduction to the importance of measurement and metrology (the science of measurement).	Martyn Sene	3 April, 2019
The role of network meta-analysis in the evaluation of antidepressants for depression	Andrea Cipriani is NIHR Research Professor at the Department of Psychiatry, University of Oxford and Honorary Consultant Psychiatrist at the NHS Foundation Trust in Oxford.	Andrea Cipriani	26 March, 2019
Why poor diagnostic reasoning is failing patients, the public and health systems	Carl Heneghan asks the question, "What is driving the increase in diagnostic testing in healthcare?" and discusses why expectations, technology and the media are contributing to the problems of too much medicine and overdiagnosis.	Carl Heneghan	6 February, 2019
Systematic reviews: the past the present and the future	Making decisions and choices about health and social care need access to high-quality evidence from research. Systematic reviews provide this by both highlighting the quality of existing studies and by themselves providing a high-quality summary.	Iain Chalmers, Carl Heneghan, Kamal Mahtani	28 January, 2019
Selection bias in cluster randomised controlled trials	Professor David Torgerson, Director of the York Trials Unit, gives a talk for the Evidence Based Healthcare podcast series.	David Torgerson	7 January, 2019
The application of realist approaches at the research/policy/practice interface: NICE work if you can do it	Professor Mike Kelly, Primary Care Unit, Department of Public Health and Primary Care, Cambridge Institute of Public Health, University of Cambridge, gives a talk for the Evidence Based Healthcare seminar series.	Mike Kelly	12 December, 2018
How imperfect can a study be?	Professor Alan Silman is an epidemiologist and a rheumatologist and is the co-author of 'Epidemiological Studies: A Practical Guide', which is the recommended textbook for the module 'Introduction to Study Design and Research Methods'.	Alan Silman	5 December, 2018
Adults' experiences of trying to lose weight on their own: findings from three qualitative syntheses	Jamie Hartmann-Boyce is a Senior Researcher in Health Behaviours, based at the Nuffield Department of Primary Care Health Sciences, University of Oxford. Her work focusses on obesity and tobacco control and her particular interests lie in evidence synthes	Jamie Hartmann-Boyce	6 November, 2018
Can antibiotics make you pregnant?	Dr Jeffrey Aronson gives a talk for the Evidence Based Healthcare series.	Jeffrey Aronson	29 October, 2018
History of evidence synthesis	Professor Mike Clarke gives a talk for the Evidence Based Healthcare series.	Mike Clarke	29 October, 2018
Evidence-Based Manifesto for better healthcare	Professor Carl Heneghan gives a talk for the Evidence Based Healthcare series.	Carl Heneghan	10 October, 2018
The jugglers and the black cat	There has never been such a high demand for our personal data, such that it is often said that individuals are the product, not just the client.	Kerina Jones	31 July, 2018
Fake surgeries and dummy pills – control for bias and study design in trials on treatment efficacy in chronic pain	In this talk Karolina presented various types of study design she has used in trials of treatments for chronic pain. Karolina also discussed why blinding is important and why a placebo control may be necessary, even in surgical trials.	Karolina Wartolowska	2 July, 2018
The shifting evidence paradigm – from literature to data	Carol Lefebvre gives a talk for the Evidence based healthcare seminar series.	Carol Lefebvre	26 June, 2018
Vagina Dialogues: Challenging Stigmas around Menstruation, Menopause and Female Sexuality	Communication taboos surround many aspects of women’s health and wellbeing, from menstruation to menopause to sexual pleasure.	Annalise Weckesser	22 June, 2018
Value-based healthcare: Health economics re-packaged or re-packaging health economics?	Sir Muir Gray and Lucy Abel debate: Is value-based health care nothing more than health economics re-packaged or is health economics nothing more than only one of the six contributors to value-based healthcare?	Muir Gray, Lucy Abel	16 May, 2018
The Replication Crisis in Biomedicine. What (kind of) crisis?	Professor Alexander Bird, Professor of Philosophy and Medicine, King's College London, gives a talk for the Centre for Evidenced Based Medicine.	Alexander Bird	11 April, 2018
Real versus rubbish EBM: do you know the difference?	A light hearted account of being treated by the 'wrong' guideline - with a serious conclusion about making sure this doesn’t happen.	Trish Greenhalgh	2 March, 2018
Launch of new website to catalogue biases affecting health and medical research	Professor Carl Heneghan and Dr David Nunan from the Oxford Centre for Evidence-Based Medicine presented the launch of a new website that catalogues the important biases affecting health and medical research.	Carl Heneghan, David Nunan, Sir Iain Chalmers	5 February, 2018
Beyond accuracy: Evidence gaps and unintended consequences. Factors influencing utility of point-of-care diagnostic tests	Point-of-care or near-patient-tests, are as these descriptors suggest, medical diagnostic tests which can be performed by a clinician, patient, or carer of a patient, without the need for samples to be transported to laboratories.	Phil Turner	30 January, 2018
Mixed methods in the real world: a messy business?	Dr Katherine Pollard gives a talk for the Evidence Based Healthcare seminar series.	Katherine Pollard	24 January, 2018
The Future of Healthcare - Evidencer and Value Based	Muir Gray is now working with both NHS England and Public Health England to bring about a transformation of care with the aim of increasing value for both populations and individuals. Here he gives a talk on improving healthcare systems.	Muir Gray	19 January, 2018
Life as a trial statistician – the good, the bad and the ugly	Professor Jonathan Cook is a Senior Medical Statistician at the Oxford Clinical Trials Research Unit.	Jonathan Cook	6 December, 2017
How we change behaviour and what to do to support it: lessons from randomised controlled trials and other research	Professor Paul Aveyard, Nuffield Department of Primary Care Health Sciences gives a talk on behavioural change in evidence based medicine.	Paul Aveyard	28 November, 2017
And then the magic happens! Can realist synthesis really be systematic?	Dr Andrew Booth gives a talk for the Realist Reviews and Realist Evaluations short course.	Andrew Booth	24 November, 2017
Working 'up' and 'out': how qualitative researchers approach analysis	Dr John MacArtney gives a talk for the Evidence Based Healthcare seminar series.	John MacArtney	15 November, 2017
A little known law of numbers	Professor Jeffrey Aronson, Consultant Physician and Clinical Pharmacologist, gives a talk for the Evidence Based Healthcare lecture series,	Jeffrey Aronson	20 October, 2017
Critical Appraisal and EBM in the Real World	The overwhelming volume of evidence and its lack of relevance to patient care and decisions means health professionals require skills to sift evidence more efficiently: discarding what doesn't make a difference to focus on evidence that matters for health	Carl Heneghan	13 October, 2017
Making trials more efficient: Trial Forge and how you can help	Trials are important; very often they are also inefficient. Trial Forge aims to improve trial efficacy by identifying and then filling gaps in trial methods research.	Shaun Treweek	10 July, 2017
Using mixed methods in health psychology: Reflections on research design, epistemology, and practicalities	In this talk, Dr Felicity Bishop will critically reflect on mixed methods research that she has conducted and discuss the philosophical and technical challenges of mixed methods.	Felicity Bishop	10 July, 2017
Better evidence for better healthcare manifesto	The integration of evidence with clinical expertise and patient values which underpins the delivery of high quality evidence-based medicine.	Carl Heneghan	12 April, 2017
Wye speling matturs	Jeffrey Aronson presents a light-hearted talk on spelling in systematic reviewing. Jeff is a Consultant Physician and Clinical Pharmacologist at the Oxford University Department for Primary Health Care.	Jeffrey Aronson	29 March, 2017
Rethinking the epidemic of overdiagnosis	Overdiagnosis is the diagnosis of "disease" that will never cause symptoms or death during a patient's lifetime. Newer, more accurate technologies, and the desire to detect disease even earlier means Overdiagnosis is on the rise.	Carl Heneghan	27 January, 2017
Resuscitating poor quality research	Healthcare research is all too often plagued by biases that are rooted in poor methods, leading to the wrong result and conclusions and preventing uptake into practice.	Carl Heneghan	17 January, 2017
Trials and Tribulations in Africa	Dr Merlin Willcox gives a talk for the Evidence Based Healthcare series.	Merlin Willcox	15 November, 2016
Better evidence for better health care	Professor Carl Heneghan gives a talk for the MSc in Evidence-Based Health Care programme.	Carl Heneghan	31 October, 2016
The point of qualitative research	Prof Aksel Tjora, Professor of Sociology at the Norwegian University of Science and Technology, gives a talk for the MSc in Evidence-Based Health Care programme.	Aksel Tjora	23 June, 2016
Evidence informed decision making? (Know your cognitive biases)	Prof Neal Maskrey gives a talk for the Centre for Evidence Based Medicine seminar series.	Neal Maskrey	1 June, 2016
Why on earth do we waste so much research?	Dr Kamal Mahtani is an NHS GP, NIHR Clinical Lecturer and Deputy Director at the Centre for Evidence Based Medicine. His talk explores why so much research is wasted.	Kamal Mahtani	1 June, 2016
Overdiagnosis and Too Much Medicine How did we get here and how do we get out of the mess	Professor Carl Heneghan gives a talk for the MSc in Evidence-Based Health Care programme	Carl Heneghan	3 May, 2016
Breathalysers, babies and bumps on the road: delving into diagnostic studies	Talk by Dr Helen Ashdown regarding three rather different diagnostic studies People: Helen Ashdown	Helen Ashdown	3 May, 2016
10 Top tips for doing applied healthcare research: How to get started	Carl Heneghan gives a talk held on January 11th 2016 Kellogg College.	Carl Heneghan	29 January, 2016
What has EBM done for healthcare?	Professor Carl Heneghan gives a talk for the Centre for Evidence Based Medicine podcast series.	Carl Heneghan	22 October, 2015
Theorising with narrative: How careful analysis of stories can help us rise above the ontological desert of ‘behaviour change’ research	Professor Trish Greenhalgh gives a talk for the Centre for Evidence Based Medicine.	Trish Greenhalgh	5 August, 2015
Managing large scale international clinical trials	Managing clinical trials, of whatever size and complexity, requires efficient trial management. Barbara Farrell shares from her wide experience.	Barbara Farrell	6 May, 2015
Storytelling in diabetes: a mixed-methods study	The patient as storyteller and the story as ‘self management’	Trish Greenhalgh	7 April, 2015
Research impact: the new jargon for knowledge to action	If we are going to take impact seriously, we need to be clear about the philosophical assumptions underpinning different kinds of research and also the different kinds of links between research, practice and policy.	Trish Greenhalgh	26 March, 2015
The Campaign for Real EBM Evidence Based Medicine	Professor Trish Greenhalgh gives a talk on the crisis facing evidence based medicine and offers a solution for its rennaissance within healthcare.	Trish Greenhalgh	24 March, 2015
From inspiration to publication: bumps along the road (as part of the Postgraduate Programme in Evidence-Based Health Care)	Dr Helen Ashdown is a GP and Clinical Researcher in the Nuffield Department of Primary Care Health Sciences, University of Oxford.	Helen Ashdown	3 December, 2014
Realist Review: Mixing Method	This talk will introduce the realist review methodology as a strategy for combining qualitative and quantitative data to answer the question “what works, for whom, and in what circumstances”	Janet Harris	1 December, 2014
Systematic Reviews, the need for change	The need to generate systematic reviews is relatively uncontroversial and until recently so were the methods of production.	Jon Brassey	1 December, 2014
EBM - What it is, what it isn't, how might you contribute?	Carl Heneghan is a Professor of Evidence-Based Medicine and a Primary Care Physician and has over 20 years experience of using evidence in practice for changing health care.	Carl Heneghan	1 December, 2014
An introduction to Medical Statistics with Carl Heneghan and Rafael Perera	Dr Carl Heneghan talks to Rafael Perera about medical statistics and gives an introduction to the subject.	Carl Heneghan, Rafael Perera	9 August, 2013
A behavioural perspective of translating evidence to policy and practice	Susan Michie, Professor of Health Psychology, UCL, gives a talk at Kellogg College for the Centre for Evidence Based Medicine.	Susan Michie	16 July, 2013
How Youtube is being used as a platform to share opinions and experiences of a controversial treatment for Multiple Sclerosis	Brandon O'Neill, DPhil Candidate, PCHS, gives a lecture on treating Multiple Sclerosis and how social media is being used to share experiences of patients.	Brandon O'Neill	16 July, 2013
Dr Carl Heneghan and John Balla discuss the evidence relating to diagnostics	Dr Carl Heneghan and John Balla discuss the evidence relating to diagnostics.	Carl Heneghan, John Balla	26 June, 2013
MSc in EBHC: Introduction to the Practice of Evidence-Based Health Care	Annette Pluddermann, Senior researcher DPCHS, gives an introduction to the Practice of Evidence-Based Health Care	Annette Pluddermann	28 May, 2013
A Welcome to the Programme in Evidence-Based Health Care	Dr Carl Heneghan, the Director of the Centre of Evidence-Based Medicine, gives a brief welcome to the Programme in Evidence-Based Health Care.	Carl Heneghan	7 February, 2013

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