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Targeting cancer mechanisms

Series
Cancer
Video Embed
Professor Robert Gilbert's research focuses on the molecular mechanisms underlying membrane pore formation and cell adhesion.
Switching mechanisms within our cells are in part responsible for their development. MicroRNAs control a whole set of proteins associated with stem cell biology, particularly cancer stem cells. Targeting these components raises the potential for new anti-cancer therapeutics, which work by switching off protein production rather than inhibiting them later.

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Melanoma or skin cancer is one of the fastest rising cancer types. When identified early, melanoma is relatively easy to cure, but once it starts to metastasise, it becomes very difficult to treat.
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Cancer

Cleaning up misfolded proteins

Misfolded proteins can either create the loss of a cellular function, or escape degradation, causing aggregation diseases.
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Licence
Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Episode Information

Series
Cancer
People
Robert Gilbert
Keywords
molecular
cell membranes
cell adhesion
cancer
stem cells
Department: Nuffield Department of Clinical Medicine
Date Added: 07/01/2016
Duration: 00:05:46

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