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Understanding growth signals

Series
Translational Medicine
Video Embed
Growth hormones and cytokines regulate the key physiological processes of growth and differentiation as well as responses to injury and infection.
FIBRODYSPLASIA OSSIFICANS PROGRESSIVA

Growth factors and signals are fundamental to many diseases. A single point mutation in the DNA coding for a bone morphogenetic protein is responsible for the development of FOP, a very debilitating disease where muscles are progressively turned into bones. Understanding these mechanisms allowed the selection of a drug, currently used to treat cancer, that may possibly be repurposed to treat FOP.

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Episode Information

Series
Translational Medicine
People
Alex Bullock
Keywords
hormones
infection
DNA
proteins
growth signals
Department: Nuffield Department of Clinical Medicine
Date Added: 28/04/2016
Duration: 00:06:53

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