Active systems, from cells and bacteria to flocks of birds, harvest chemical energy which they use to move and to control the complex processes needed for life.
A goal of biophysicists is to construct new physical theories to understand these living systems, which operate far from equilibrium. Topological defects are key to the behaviour of certain dense active systems and, surprisingly, there is increasing evidence that they may play a role in the biological functioning of bacterial and epithelial cells.